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Hyaluronic acid: different weights, different effects

The molecular weight of hyaluronic acid affects its biological functions and tissue penetration after delivery.
For this reason, not all hyaluronic acids have equivalent functions.


It is the native form of hyaluronic acid. High molecular weight hyaluronic acid is similar to the one our body produces and its production decreases with aging.
After delivery of high molecular weight, the skin is revitalized and optimally hydrated, and its smoothness, elasticity, and tone improves, thanks to its hydrating and protective effects.

For this reason, the HIGH molecular weight hyaluronic acid applied to the skin acts on the surface.


It penetrates into the deep layers of the skin and stimulates production of collagen.
The skin regains density and firmness and the depth of existing wrinkles is diminished.

For this reason, the LOW molecular weight hyaluronic acid acts in the deepest layers of the skin.


Forms hydrogels that create a protective film on the surface of the skin.
Cross-linked hyaluronic acid is more stable to enzymatic degradation and, in case of treatment with fillers, it maintains its effects over time. Skin wrinkles are rapidly reduced, and the anti-aging and moisturizing effect is long lasting.

Increased stability of CROSS-LINKED hyaluronic acid from enzymatic degradation prolongs its beneficial effects to the skin.

It is therefore necessary to choose the type of hyaluronic acid that is more suitable to achieve the desired cosmetic goals.

The maximum efficacy of hyaluronic acid is obtained by combining these three different types of hyaluronic acid that act synergistically.
Eye Pharma was able to create a formula containing high molecular weight, low molecular weight, and cross-linked hyaluronic acid, to provide a complete and long-lasting moisturizing action at different levels of the skin.

Scientific research on skincare helps perfect ingredients and understand the specific actions behind each key component of a cream formulation.

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