Unhealthy lifestyle and eating habits have been considered the main risk factors for the development of diabetes, a serious health condition.

Diabetic retinopathy is a diabetes complication caused by microvascular damage associated with hyperglycemia.

Diabetic retinopathy is classified as proliferative or non-proliferative according to the presence or absence of pathogenic angiogenesis.

Retinopathy can also have disabling consequences when it is  associated with ischemic episodes and  lack of oxygenation of the retina. One of the most dangerous effects of retinopathy is the development of diabetic macular edema.

Diabetic macular edema consists of fluid extravasation into the macula, which significantly alters the quality of vision (blurred, wavy vision, or altered colors), often irreversibly.

To prevent the dangerous progression of diabetic retinopathy it is necessary to intervene therapeutically on several fronts.

From a therapeutic perspective, it is imperative to take immediate action to stop progression of macular edema, due to the serious and irreversible vision damage that it can cause.

Thus, therapeutic management of the patients need to restore the tissue balance altered by hyperglycemia by acting on several fronts.